Vaccine

Does "obtuse" stretch enough to cover this?

"There is a lack of consensus among society and organizational guidelines on whether remdesivir should be used in the management of COVID-19, given the varying results in existing clinical trial data."
Weird that its a recommended treatment by the NIH. So are your saying that the NIH is recommending bullshit treatments? Who should we listen to then? Your cherry picked sources?

 
Remdesvir is an accepted and widely used treatment for Covid by reputable hospitals and doctors.

There are issues that limit its effectiveness. It has to be bioactivated, and it is short lived in circulation. Those are things that the chemists can work on. But there is a also a legitimate debate as to whether it enhances the rate of viral genetic changes, and, for other viruses, drug resistant variants can be selected. But it is nice to have a drug in the arsenal that targets something besides the spike protein. Remdesvir and related drugs occupy that niche.
 
Ivermectin. Remdesivir intended action to directly block the polymerase of RNA viruses, thus blocking the viral replication cycle.

Your description of a non-effective prophylactic that might reduce viral load once infected seems to apply to both Ivermectin and Remdesivir, mechanics of how that may be accomplished aside.
 
As is the case for most things - good studies needed to be performed, without media and political influcence Stuff coming out of cornell, in preprint shows promise VS omicron, outperforming other medications on the market. At a minimum, ivermectin's anti inflammatory properties will aid in recovery and possibly prevent/protect against organ damage. Prescribed and admnistered correctly, there is more potential upside with minimal to zero downside. It's one of the safest known prescribed medications on the planet. But don't tell anyone that.

Would I 100% rely on ivermectin as treatment and prevention..uhh, no. In most cases drs treat disease as a whole. Trying to do basic math and adminstering it from the feed store is never a good thing, unless you are decent at math. I'd be more concerned with people taking other's left over corticosteroid prescription

One thing to know is that there is much incentive in the pharmaceutical industry to repurpose drugs. There are a number of reasons, with the main one being that a repurposed drug does not need to go through the same sort of FDA approval process, which makes it much cheaper to bring to market for a new application. I can guarantee you that there are studies throwing chemical libraries with known drugs looking for compounds that block Ace2 binding to spike. Something that actually can get into the airway side of the aveolar sacs. The work is already there showing that, at very high concentration, ivermectin can block Ace2-spike. In fact, because of its structure, it can block many protein-protein interactions because of its structure, sort of non-specifically. But delivering ivermectin to the aveolii at the necessary concentration to block that interaction in people is not a trivial matter-getting a big chemical structure drug across that membrane is just tough. You need a very high circulating concentration for that to even be possible. And at those concentrations it gets into the CNS and is a rather potent neurotoxin. If CoV-2 were an enteric virus it might be a different story. Omicron has acquired changes allowing it to infect the upper respiratory tract, so a nasal spray form of ivermectin might be something to try. Don't know if its been looked at it.

The public health push was always going to be directed towards something that could actually confer immunity. A drug approach does not make that possible. But taking ivermectin at proper dosage certainly will not hurt you, and it could conceivably have some benefit on the post infection side. The anti-inflammatory properties, to my understanding, have been mostly looked at with respect to reducing the mortality of full blown COVID19
 
Your description of a non-effective prophylactic that might reduce viral load once infected seems to apply to both Ivermectin and Remdesivir, mechanics of how that may be accomplished aside.

Remdesivir has been approved by the FDA for treatment of COVID19. It needed to show efficacy to get that designation. There will likely be a second generation of nucleoside analogue drugs that work better.
 
"There is a lack of consensus among society and organizational guidelines on whether remdesivir should be used in the management of COVID-19, given the varying results in existing clinical trial data."

Agreed. Now insert any other treatment name in place of remdesivir in that quote and I’ll also agree with that as tautology.
 
One thing to know is that there is much incentive in the pharmaceutical industry to repurpose drugs. There are a number of reasons, with the main one being that a repurposed drug does not need to go through the same sort of FDA approval process, which makes it much cheaper to bring to market for a new application. I can guarantee you that there are studies throwing chemical libraries with known drugs looking for compounds that block Ace2 binding to spike.

I can not agree that is accurate statement about “much incentive in the pharmaceutical industry to repurpose drugs” when discussing a drug that is out of patent… but you knew that.

The opposite is true of poor nations and humanitarians that just want to save lives as cheaply as possible. Ironically, where some medications are accepted more frequently.

I’m certainly not pushing ‘horse paste’ (that makes me laugh as I actually do my own body weight calculations on the Equine Dewormer, fenbendazole, for my canines veterinary purposes), or bleach.
 
I can not agree that is accurate statement about “much incentive in the pharmaceutical industry to repurpose drugs” when discussing a drug that is out of patent… but you knew that.

The opposite is true of poor nations and humanitarians that just want to save lives as cheaply as possible. Ironically, where some medications are accepted more frequently.

I’m certainly not pushing ‘horse paste’ (that makes me laugh as I actually do my own body weight calculations on the Equine Dewormer, fenbendazole, for my canines veterinary purposes), or bleach.

thought the approval was for a medical application, and that approval persists after the end date of the patent. generic branding would seem to depends on it. and if you find a new application for an old drug you can get a patent for that with a fraction of the R&D cost. no? people who try to save lives-good on them. you use the tools you have.
 
Shoot the messanger and ignore the message in 3..2..1

"Dr. Long also testified that the data shows that deaths of military members from the vaccines exceed deaths from COVID itself."

 
Shoot the messanger and ignore the message in 3..2..1

"Dr. Long also testified that the data shows that deaths of military members from the vaccines exceed deaths from COVID itself."

Your article refers to “certain disorders spiked after the vaccine mandate went into effect, including miscarriages and cancers, and neurological problems which increased by 1000 percent.”

You expect us to believe that we had a ten fold increase in cancer and neurological disorders among vaccine recipients, but no one noticed? Ten fold increase, caused by a shot received by 2/3 of the population.

So, this epidemic of cancers and miscarriages has been going on for over a year. At a rate 10X as high as 2 years ago. You’d think someone in oncology would notice the fact that they are a wee bit overworked recently.

People tend to notice when their workload increases tenfold. There is that moment when you look up and think “I haven’t had a day off in seven months. Maybe something is wrong…”

Golly. It’s one humdinger of a mystery. Wonder how they kept it hidden for so long.
 
thought the approval was for a medical application, and that approval persists after the end date of the patent. generic branding would seem to depends on it. and if you find a new application for an old drug you can get a patent for that with a fraction of the R&D cost. no? people who try to save lives-good on them. you use the tools you have.

Yup, that is also true. Look, I don’t want to give fodder to those that want to draw inaccurate concussions and mislead others… I assume you have a similar inclination given your somewhat dispassionate responses, but I think you and a few others in this forum get my point and I’ll leave it at that.

BTW, I found this recent article interesting…


Sounds similar to something that was debated previously on this forum.

“Some observers have noted that the U.S. is recording fewer PCR test results now than it was then, in large part because at-home antigen tests — which usually go unreported — are more widely available. “A lot of people are rapid-testing positive for mild cases of COVID, staying home for a few days, getting better, and getting on with life,” the Atlantic’s Derek Thompson noted Thursday. “This cycle makes no contact [with] official data.” Thompson called it “an invisible wave.””
 
Your article refers to “certain disorders spiked after the vaccine mandate went into effect, including miscarriages and cancers, and neurological problems which increased by 1000 percent.”

You expect us to believe that we had a ten fold increase in cancer and neurological disorders among vaccine recipients, but no one noticed? Ten fold increase, caused by a shot received by 2/3 of the population.

So, this epidemic of cancers and miscarriages has been going on for over a year. At a rate 10X as high as 2 years ago. You’d think someone in oncology would notice the fact that they are a wee bit overworked recently.

People tend to notice when their workload increases tenfold. There is that moment when you look up and think “I haven’t had a day off in seven months. Maybe something is wrong…”

Golly. It’s one humdinger of a mystery. Wonder how they kept it hidden for so long.

Dr. Long has claimed that the vaccines contain antifreeze. Maybe that is to prevent damage to Bill Gates' microchips.
 
Is that one of the doctors for America like the voodoo witch doctor lady from Houston?
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Look in her eyes and ask yourself what you see Husker? Look deeply into her eyes. The super sharp Doctor from Houston knows my Doc and they both saved lives with sound medical advice. One size does not fit all. Options and lot's of opinions are good. I went with no meat and no booze and no TV and a healthy life with my wife, which allows my God given immune system to do the rest. Some choose jabs + boosters and eat whatever they want and drink themselves to sleep with booze and pills. Some chose a jab and then stopped after the first jab or second and got healthy like me. It's all a choice. We do have some choice still what we inject into our blood? Alternative medicine will be the new normal. Wellness, not illness!!!
 
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Moderna just recalled over 760,000 jabs because some doses was found to be contaminated with a foreign body. Japanese health pros suspended the same doses last year because they found stainless steal in a vial. Also, little pieces of plastic found in people's blood. That is why people have blood clots like the common cold now. This is coming out of Reuters. Also, old pal took two jabs of this stuff and is sick all the time and has shortness of breath. He is getting his blood looked at. My nephew had a Widow attack and one of my old pastors sister died. I also said old teacher pal got blood clots and is on blood thinner and my other pals wife is on pace for another record year selling drugs. My old house in Temecula is worth over $800,000 now......lol!
 
Difficult Truths will soon see the Light of Day! Dark to Light! The enormity of what is coming will SHOCK the world. Pray!!!
 
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