Compared to what number(s)?
Depends how you want to measure it. Compared to zero it's a huge number if you slice it against total world population (it's also BTW a lot of random 40 year olds cut down in the prime of their life, even though overwhelmingly 40 year olds will be just fine). You can also take it by years of life expectancy lost, in which case the number is much much smaller.