Vaccine

Grace, there's a reason (actually more than one) for why the effective vaccines against SARS-CoV2 are focused on the spike protein, and not on trying to give the immune system a wide range of different protein targets to sample. It is also partly why the monoclonal antibody treatments for mild-moderate covid are directed only against the spike protein.

Maybe a soccer analogy would help? Let's see, your team has to defend against a PK, and in this game, the rules are such that you can add 10 additional players to try to defend against the PK. I'm going to guess that you would want to add 10 goalkeepers in goal, rather than place 10 other players all over the field. Maybe someone else has a better soccer analogy.....

I'm struggling to come up with one. Correct me if I am wrong, but it seems to me that concentrating on the spike protein makes sense because that is the part of the covid exterior that is most unlike any other passive organism the vaccine-induced antibodies might encounter. Perhaps a different soccer analogy is that if you know the PK shooter always shoots low and to his left, you defend against that.
 
Here's the counter position to the booster. It's going to scare the shit out of dad 4 and the others on team panic. I posted the Gottleib position above. This is the contra. I don't know which is right, but note Campbell who did this review has been pro NPI pro vaccine.

The counter argument going around to boosters forever, at least for the non-elderly, non-immunocompromised, is that there has been quite a bit of data coming out that natural immunity is actually more robust than vaccine immunity just because it operates in a variety of different ways to stop infection, while the vaccines only operate on the spike protein. So, it is possible that for the non-elderly, non-immunocompromised, which will need boosters perhaps multiple boosters, is that while vaccine immunity is at its highest, the best thing we can do to end this is TO ACTUALLY HAVE PEOPLE EXPOSED AND/OR INFECTED with the virus. That has enormous implications including: 1) children should not be vaxxed...if the vax doesn't stop disease or even massively reduce hospitalizations, since they don't suffer from the severe form, it's probably better for them, particularly the under 12, to just get repeated exposures to the virus, 2) people while at a high level of immunity from the vaccine would need to risk natural exposure, 3) NPIS such as masks and dining/crowd restrictions are actually counter productive to ending the pandemic and is just prolonging the misery.

Like I said, Campbell is not an antilockdown nut and he cites the thinking of experts, particularly those that have the ear of the UK government. He even has his mask poster behind him. I don't know who is right....this position or the Gottlieb position. I do find it funny however that either choice represents a binary choice of either the CDC f'ed up with the vaccination protocol (if Gottlieb is right) or the CDC is screwing up now by recommending masks/limitations (if the experts Campbell cites are correct). Again, I'm not sure who is right at this particular point and am open minded either way. I do note if Gottlieb is right it means we are going to be dealing with this for at least 4 to 5 years. If Campbell is right, this is endemic and a cold by next year, assuming the experts don't f it up and waste this time.

But I know someone who won't be happy if Campbell is right (yeah it's several of you, let me apologize in advance but it's just too funny)....cue dad4 freakout in 5 4 3 2 1

As I've posted before, Campbell is not saying anything new regarding natural immunity. Except Mrs IZ is going to hate that I'll not be clearing the thickets from my nostrils anytime soon. As long as I can still see through them when I'm driving, I'll be good. I loved Vaxspola's responses. A lot of nothingness for having watched the video. I love watching him argue as an M.D., epidemiologist or any of the other titles that he has attributed to himself.
 
I'm struggling to come up with one. Correct me if I am wrong, but it seems to me that concentrating on the spike protein makes sense because that is the part of the covid exterior that is most unlike any other passive organism the vaccine-induced antibodies might encounter. Perhaps a different soccer analogy is that if you know the PK shooter always shoots low and to his left, you defend against that.
I watched the video. He doesn't say what you said he did. You have done that more than once when linking his videos. It ends up being your opinion of his opinions of articles. Did you ever play the party game Gossip or Telephone?
Tell us about them Gamespola.
 
I thought my preaching days were over when things got nasty in 2017. However, I'm back with a smile and message. Open your brain and let the dear savior in. It will unlock the key to the other 95-90% of the brain you dont use. Some on here are using only maybe 3% from my guess.
I will share good gospel news from time to time to help you who have no faith.
God News Sharing: My pal Ryan was going through some tough times last year at this time in California. He had to move back to Ohio because the company he worked for went OB because of the pandemic. He was sad to leave but someone poked him about what life is really about for the two years he was here. He just got baptized and thanked me for the pokes. Espola, Husker, Evil, Dad of 4 kids, Messy, EOTL and the New Roadrunner, this song is for you. My dad's eyes were opened before he died and it's "never too late to capitulate." it's never too late to see the light fellas. This songs for you guys,

 
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All I can say man is that is the Campbell video turns out to be correct you will have completely chumped out dad 4 and blown my mind…you will have been more right than him (or me for that matter)
That's not saying much when you consider the history of viruses that I've posted about and that has been largely ignored by Dadspola, Docspola, and Hus pola et al.
 
Writing in Spiked, Martin Kulldorff and Jay Bhattacharya decry the smear campaign against the Great Barrington Declaration. Two slices:


In October 2020, along with Professor Sunetra Gupta, we authored the Great Barrington Declaration, in which we argued for a ‘focused protection’ pandemic strategy. We called for better protection of older and other high-risk people, while arguing that children should be allowed to go to school and young adults should be free to live more normal lives. We understood that it might lead to vigorous and heated discussions, but we did not expect a multi-pronged propaganda campaign that gravely distorted our arguments and smeared us. We are just three public-health scientists, after all. So how and why did this slanderous counterattack emerge?

In his recent book, Spike, Jeremy Farrar – a SAGE member and director of the Wellcome Trust – has provided a helpful hint: the political strategist and the prime minister’s chief adviser, Dominic Cummings, planned a propaganda campaign against the Great Barrington Declaration. Farrar’s exact words are that Cummings ‘wanted to run an aggressive press campaign against those behind the Great Barrington Declaration and others opposed to blanket Covid-19 restrictions’. Cummings and Farrar preferred a blanket lockdown strategy, believing it would avoid a winter Covid wave.

…..

[Matt] Hancock, Anthony Fauci, Jeremy Farrar and prominent journalists also mischaracterized the Great Barrington Declaration as a ‘herd-immunity strategy’, even though any strategy will lead to herd immunity sooner or later. Yes, the Declaration discussed herd immunity. It would be irresponsible to ignore such a basic biological fact. But to characterize the Great Barrington Declaration as a ‘herd-immunity strategy’ is like describing a pilot’s plan to land a plane as a ‘gravity strategy’. The goal of a pilot is to land the plane safely while managing the force of gravity. The goal of any Covid pandemic plan should be to minimize disease mortality and the collateral harms from the plan itself, while managing the build-up of immunity in the population. Shockingly, some politicians, journalists and even scientists denied the very existence of herd immunity. Some even questioned the existence of natural immunity from Covid, which is a bit like denying gravity.
 
Ah I thought you were attacking the messenger Campbell. So if I’m mistaken sorry for that. But if you’ve read the papers then what are your opinions on the Uk approach?

Grace, I was correcting the assumption you made about my reaction to the video. I'm not attacking any person, but I did criticize the video.

As to the question of what is the best policy for governments to pursue? I'm sure that depends on the situation in their particular area. It also depends on what the goals are of the government or other group setting the policy. It's complex, as many on here have discussed.

From the biology side, knowing just how destructive this virus can be once set loose in our bodies and the damage that an infection can lead to, if given a choice, I would not want anyone to get infected. There's also the risk that a variant with a high mortality rate could emerge. No one can know whether this will or won't happen. This, I would advise against choices where the virus is permitted to thrive.
 
Some even questioned the existence of natural immunity from Covid, which is a bit like denying gravity.
Gravity is still a theory last I heard. No one here is ready for that discussion so I wont bring that up anymore. Were still here arguing if God is real with the scared men. Once we ALL see God is the great I AM, then we can move unto Real Science and Religion for $1,000, not Science Magicians and Weird Science for $1.
 
At least some Australians are actively resisting the thugs who govern that once-free country. (DBx: Note that Victoria’s premier, Dan Andrews, declared that Friday’s 61 new cases [cases, not deaths] of Covid in that state – a state with a population of 6.7 million – portends “catastrophe.” On Friday, the seven-day average of new Covid-19 cases was a whopping 39. Sixty-one is 0.00091 percent of Victoria’s population; 39 is 0.00058 percent. [There’s been no Covid death in Victoria since October 27th, when two people died.] When government gets to define such a situation as a “catastrophe” in the making, and then to use this ‘evidence’ of a coming “catastrophe” as an excuse to unleash unprecedented restrictions on freedom, restrictions enforced with unprecedented powers, tyranny has truly arrived. Meanwhile in Sweden, the seven-day average of Covid deaths is now one.)
 
As to the question of what is the best policy for governments to pursue? I'm sure that depends on the "Political" situation in their particular area ((where you live)).
I added a word in red. It 100% depends on the "political" situation and are where you live Rr. None of this is true anymore. The gig is up. Your side cheated and got caught. The bribes and blackmail will shock you to the core. You will be sick and depressed because you voted for a lie and evil team of evil doers. Killing babies and then selling their parts is evil to the core. No one will escape the truth. Good people who were tricked will need to see that for what it is and then learn from it and make sure not to ever be tricked again.
 
Grace, I was correcting the assumption you made about my reaction to the video. I'm not attacking any person, but I did criticize the video.

As to the question of what is the best policy for governments to pursue? I'm sure that depends on the situation in their particular area. It also depends on what the goals are of the government or other group setting the policy. It's complex, as many on here have discussed.

From the biology side, knowing just how destructive this virus can be once set loose in our bodies and the damage that an infection can lead to, if given a choice, I would not want anyone to get infected. There's also the risk that a variant with a high mortality rate could emerge. No one can know whether this will or won't happen. This, I would advise against choices where the virus is permitted to thrive.
Zero covid is not one of your choices. It’s neither the Gottlieb or uk approach. China australia and New Zealand are still clinging to the fantasy of zero covid and you can see how that’s going. Believing in zero covid given how the vaccine is performing is a fantasy

neither is the no further variant possibility because most of the world won’t be vaccinated until 2023.

further you forwarded nothing to support your assertion the virus is “destructive” among the vaccinated…and if so you would be saying the vaccine is at least a partial failure

I asked for your opinion as to the two approaches and you threw up two fantasies. Slightly disappointed as you struck me as thoughtful.
 
Zero covid is not one of your choices. It’s neither the Gottlieb or uk approach. China australia and New Zealand are still clinging to the fantasy of zero covid and you can see how that’s going. Believing in zero covid given how the vaccine is performing is a fantasy

neither is the no further variant possibility because most of the world won’t be vaccinated until 2023.

further you forwarded nothing to support your assertion the virus is “destructive” among the vaccinated…and if so you would be saying the vaccine is at least a partial failure

I asked for your opinion as to the two approaches and you threw up two fantasies. Slightly disappointed as you struck me as thoughtful.
Ps my 12 year old and I just had this fight. “You can have Mexican or bbq for lunch”. “I want crawfish”. “Sorry dude they just went out of season…how bout versailles”. “I want crawfish”. “Sigh”.
 
At least some Australians are actively resisting the thugs who govern that once-free country. (DBx: Note that Victoria’s premier, Dan Andrews, declared that Friday’s 61 new cases [cases, not deaths] of Covid in that state – a state with a population of 6.7 million – portends “catastrophe.” On Friday, the seven-day average of new Covid-19 cases was a whopping 39. Sixty-one is 0.00091 percent of Victoria’s population; 39 is 0.00058 percent. [There’s been no Covid death in Victoria since October 27th, when two people died.] When government gets to define such a situation as a “catastrophe” in the making, and then to use this ‘evidence’ of a coming “catastrophe” as an excuse to unleash unprecedented restrictions on freedom, restrictions enforced with unprecedented powers, tyranny has truly arrived. Meanwhile in Sweden, the seven-day average of Covid deaths is now one.)
Paris is pissed

 
Hypothesis: the majority of people currently taking offense at analogies between lockdowns and the Taliban (or North Korea or other similar authoritarian regimes) are doing so primarily because these comparisons hit a little too close to home for their own comfort.

Yes, the comparisons involve a degree of hyperbole and intentionally so. But there’s more than enough of an authoritarian flavor to lockdowns, to the ways they were enacted, and to the basic curtailment of freedom that they entail to place them in the same ballpark as the types of policies that we usually associate with third world dictatorships or communist regimes.

Of course we also know that most of the offense taken here is feigned precisely because the very same people who get outraged at these comparisons spent the last 1.5 years indulging in far more severe hyperbole by likening even modest expressions of skepticism about lockdowns and masks to eugenics, ethnic cleansing, racism, and attempted murder.--Phil Magness
 
Monsters of fear. Look at this you guys.


This is what Dad is advocating because his life is a life of being controlled with fear. It's a drug of adrenalin made from our brains and causes people to make decisions caused by the fear their brain makes. Once the brain makes fear, the mind plays tricks on your greatest fears and makes many of you to tell stories that you make up in your freaking head. None of us know what tomorrow will bring. Think about that why I go and pray and mediate on my lesson for today.
 
Hard to convince the pro-vax folks that comparing a single event to itself is not as scientific as is comparing it to the science of past respiratory viruses that have evolved with us. They are not open to the possibility or probability that we would not be a world population of nearly 7 billion and growing if not for viral updates via viruses. Duh!
To be clear I'm pro-Vax but I'm also pro-immunity from prior infection. The available evidence indicates that natural immunity is stronger than vaccinated immunity, likely substantially stronger. I'm pro-choice.

To require proof of vaccination is incredibly discriminatory and gross government overreach. I don't think you should require any proof, but it would be far more appropriate to have to provide proof of either a vaccination or prior infection. Even then you still run into discriminatory issues due to the fact that some races have low vaccination rates.
 

@ Dad of 4 kids, watch this short video. I bet Father of Lies Espola will watch to fact check if this is a true video. This is from a real doctor. You can;t trust anyone if all they do is lie for political gain. All the kids are pawns and those who have a few questions are being controlled, locked out and kicked out of all that life has to offer and it's pure evil. Science Magicians. No need for a mask at all according to so any, if Dr. F said their is no need for a mask. Bruddah IZ, we need your fact sheets. Keep bringing them bro. Me & Grace and anyone with an honest brain and a heart full of gold can see the truth. Liars only lie. They just talk lie. Lying is it's own language btw. Thank you for showing us the truth IZ. The Father of Lies has been lying and making pawns out of kids. Sickos and Espola is here 24/7 with no kids. Imagine an old man on here with no kids in the game. Why? These men are full of darkness. Their hearts are so hard and their eyes are blind and their ears are clogged with bullshit from the BS in their brain. True losers in every sense. Their time is up. Nowhere to hide. The Light is never going away but the darkness and those who live in darkness will be no more. Can I get a hallelujah and a Amen? They make fun of all that has happen in the war for the last 20 years and just chalk it up as an, "oh well." They mock our soldiers who lost legs. They mock those WHO think for themselves. Their scared little men who face judgement like at no other time. Judgement is coming and it will be swift. The game is over and now you must answer to the One.
Surgeons are trained to think of masks as PPE. Make sure the patient does not infect the doctor. Make sure the doctor doesn’t place germs into the patient’s open wound. Important stuff. Just not relevant to the question of masks for going to the grocery store.

Asking a surgeon about epidemiology is no more helpful than asking an epidemiologist to remove your appendix. Each has their own area of expertise, and neither one knows how to do the other’s job.
 
I'm struggling to come up with one. Correct me if I am wrong, but it seems to me that concentrating on the spike protein makes sense because that is the part of the covid exterior that is most unlike any other passive organism the vaccine-induced antibodies might encounter. Perhaps a different soccer analogy is that if you know the PK shooter always shoots low and to his left, you defend against that.

Yes. Plus two other key things make spike the most obvious vaccine target. First, spike acts on the outside of the cell to mediate the first step in the infection cycle. Once the virus gains cell entry, all other viral protein surfaces are masked from the immune system. Second, since it projects away from the viral capsid surface, it presents an effect surface area to which neutralizing antibodies can bind.
 
Asking a surgeon about epidemiology is no more helpful than asking an epidemiologist to remove your appendix. Each has their own area of expertise, and neither one knows how to do the other’s job.
Not sure about your analogy, but regardless I strongly disagree with your point. It touches on the expert arrogance that I've pointed out a number of times. A surgeon may have a much broader view and is entitled to question the conclusions of an epidemiologist. We're all entitled to question or take advice counter to an expert. We're entitled to our choice.

-We were against the doctor doing an amnio, he repeatedly assured us that it was safe. It wasn't it....it resulted in a crash c-section, my daughter to be resuscitated at birth, a scalpel cut across her head, 6 weeks premature
-My dad had been to just about every doctor including the Mayo clinic for a number of years. No diagnosis other than possible dehydration. I diagnosed it as Parkinson's, which was thereafter confirmed by a doctor
-The anecdote about my mom telling the doctor that my dad need to be hydrated

Sorry, I'm not going to delegate my medical decisions to an "expert". I will strongly consider their input, along with 2nd and likely 3rd opinions. I'm not going to get a vaccination just because an epidemiologist recommends it, and surely not because a politician requires it. I will, and did, consult with my doctor before making that decision.

You should get multiple medical opinions before making any serious decision. I think your an idiot if you don't, but hey its your choice. Let Darwin sort it out like Nova.Dad's examples likely point out.
 
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