Bad News Thread

It isn't even close to 50% anymore. Walk into any store, etc. The person wearing the mask is now the oddity...and is probably vaccinated as well.
and the one's whining and crying over the fact they jumped first in line. I have to deal with the same folks. They will always hate me because I dont agree with them about anything with regards to science. It's come down to my way or the highway. These asshats are ruining our lives because.......
 
Newsom says state employees and health care workers must vaccinate or test weekly.

Newsom is going to be placed under an enormous pressure to do something further by his health advisors. Even though he is still in a comfortable (48/43) lead in the recall his enthusiasm rating is down and 54% of voters want a new governor 2022. Rock and a hard place for him.

Which polls?
 
Compared to the prime of life, as we age the stem cell populations in our body that get expanded to produce an antibody response inevitably decline. Mounting an active, acquired immune response (ie the ability to remember what you've been exposed to in the past and then producing the antibody response if re-challenged) becomes increasingly difficulty. Clean smart living can slow the decline, but within limits.

My take is the fear industry is largely self-manufactured, and is then exploitable, rather than the other way around. Look at the last two weeks of this thread. We are are on the downside of a global pandemic. In some ways we've been so, so lucky, but we did sorta-kinda manage to buy time for vaccines and those appear largely successful so far. First time in history. And yet its all about economic ruin, the tyranny of masks, why not bring in climate change too, government herding the sheeple, all that stuff. Don't really get it, but then I never liked "Goosebumps" either.
Oh don't you worry. The fear merchants will be dragging in that dead cat climate soon enough.
 
Can we get to “zero”? It depends on which question you are asking and what assumptions you make.

Could we get to zero deaths per day? Absolutely. It would take 12 months and near universal vaccinations.

Can we get to zero cases while we all take our unvaccinated, unmasked selves out for dinner? Heck no.

Now, which question were you asking? Zero deaths by behaving well, or zero cases by behaving foolishly?
Too bad you clowns are trying to build your case based on the PCR test. Getting to zero? Not gonna happen with the PCR test.
 
Too bad you clowns are trying to build your case based on the PCR test. Getting to zero? Not gonna happen with the PCR test.
Espola still has me on Ignore Bruddah. He got all upset with me a couple years ago because I told him the truth and he doesnt like it when the truth hurts.
 
IFR varies for different segments of the population. Assuming R0 of 2 (which is low for delta) for 18-49 yr with this virus its IFR 150/1000000 = 0.0002. For 65+ the IFR is 0.026, 130X higher (both numbers from CDC). That higher IFR is going to include seniors who have taken care of themselves and those that have not. Like you say, simply being alive for a long time imposes long term damage and increased susceptibility. So the collective approach assumes the 0.0002 crowd will go along with public health policies to protect the 0.026 crowd. I don't think there's a hard number for what the IFR is for vaxxed 65+, but it will almost certainly be greatly reduced. So was that worth it?
We've been here before. No I don't think there is a hard IFR number for vaxxed 65+ but we've not changed infection rates with vaccines for at least the last three decades. We've decreased time of symptoms by maybe 4 to 6 hrs. So are those facts worth shutting down the global economy and denying folks access to therapies that could've saved their lives?


A global pandemic was always going to be scary, but you are also right in that we could have from the get go gone to herd immunity without any guardrails. But that's a value issue and with all such things everybody will see it through one lens or another.
A global pandemic was not always going to be scary if you consider the definition of a pandemic. We've had 13K+ pandemics since 1978. When a virus makes it to two continents it is considered a pandemic.
 
Newsom says state employees and health care workers must vaccinate or test weekly.

Newsom is going to be placed under an enormous pressure to do something further by his health advisors. Even though he is still in a comfortable (48/43) lead in the recall his enthusiasm rating is down and 54% of voters want a new governor 2022. Rock and a hard place for him.
Newsome is a coward.
 
We've been here before. No I don't think there is a hard IFR number for vaxxed 65+ but we've not changed infection rates with vaccines for at least the last three decades. We've decreased time of symptoms by maybe 4 to 6 hrs. So are those facts worth shutting down the global economy and denying folks access to therapies that could've saved their lives?


A global pandemic was not always going to be scary if you consider the definition of a pandemic. We've had 13K+ pandemics since 1978. When a virus makes it to two continents it is considered a pandemic.
My wife just told me the unwaxed are now being compared to drunk drivers. I'll just stay home from now on until the dust settles. I really dont know what to do Bruddah. This is NOT FDA approved and so experimental that I just can;t do it.
 
PCR test. Getting to zero?

If you don't like the PCR test alternatives could be devised. I'm thinking a line of immuno-compromised, human ACE2-adapted gerbils. French kiss 10 and see how many die. Of course you'll also need to kiss 10 non-adapted controls to get a meaningful ratio. If you come at them coughing and hacking 9 times out of 10 they'll bite down hard cause their gerbil spidy sense tells them what's coming.

There's a variant of PCR called QPCR that is not just a + or - assay. For some of the potential test populations that Dad4 mentioned eariler QPCR would allow a quantitative view of viral load with or without the vaccine in either sympotmatic or non-sympomatic people. So you would have some basis for distinguishing "cases" from "infections". Which is the issue.

And its important to come to the sense that by any objective criterion the virus has already won. It has spread itself around the globe. It will now burn itself down into non-zero equilibria in our populations, with the burn rate determined by what we do. That's evolutionary success for the virus. Short of a jump to another host, the numbers will be much lower. But it isn't going away.
 
If you don't like the PCR test alternatives could be devised. I'm thinking a line of immuno-compromised, human ACE2-adapted gerbils. French kiss 10 and see how many die. Of course you'll also need to kiss 10 non-adapted controls to get a meaningful ratio. If you come at them coughing and hacking 9 times out of 10 they'll bite down hard cause their gerbil spidy sense tells them what's coming.

There's a variant of PCR called QPCR that is not just a + or - assay. For some of the potential test populations that Dad4 mentioned eariler QPCR would allow a quantitative view of viral load with or without the vaccine in either sympotmatic or non-sympomatic people. So you would have some basis for distinguishing "cases" from "infections". Which is the issue.

And its important to come to the sense that by any objective criterion the virus has already won. It has spread itself around the globe. It will now burn itself down into non-zero equilibria in our populations, with the burn rate determined by what we do. That's evolutionary success for the virus. Short of a jump to another host, the numbers will be much lower. But it isn't going away.
Way too late to ask for alternatives bro. Think about what your saying here, my gosh. They jacked up test results to create fear on all of us around the world. The dude that invented the test warned all the Docs not to use it to pad their numbers. Dude is dead now too so this is scary shit. Like I said so many times, I'm past 9 lives so I dont care. I'm now offically accused of being a drunk driver. Gee, I feel so special now. My best pal tells me I remind him of a cat because I keep landing on my feet when I fall. I used to get so many mean PMs on this site from lawyer dudes and asshole dads in soccer that wanted me to STFU. Anyway, be very careful what type of liguid your willing to shoot up with. My other pal is from Stanford and knows his stuff way more than anyone on here and I'll listen to him and him alone. Talk about a smart cat and is also a real Doctor that gives real advice.
 
If you don't like the PCR test alternatives could be devised. I'm thinking a line of immuno-compromised, human ACE2-adapted gerbils. French kiss 10 and see how many die. Of course you'll also need to kiss 10 non-adapted controls to get a meaningful ratio. If you come at them coughing and hacking 9 times out of 10 they'll bite down hard cause their gerbil spidy sense tells them what's coming.

There's a variant of PCR called QPCR that is not just a + or - assay. For some of the potential test populations that Dad4 mentioned eariler QPCR would allow a quantitative view of viral load with or without the vaccine in either sympotmatic or non-sympomatic people. So you would have some basis for distinguishing "cases" from "infections". Which is the issue.

And its important to come to the sense that by any objective criterion the virus has already won. It has spread itself around the globe. It will now burn itself down into non-zero equilibria in our populations, with the burn rate determined by what we do. That's evolutionary success for the virus. Short of a jump to another host, the numbers will be much lower. But it isn't going away.
Maybe we could get a test that gives us a time stamp for when the corona genetic sequences showed up in those tested. You know, since corona and other respiratory virus have been around for nearly 800 years? That we know of. We seem to have evolved with them. Our existence through viral updates?
 
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