Vaccine

[Grace T.]

I can appreciate the desire for better candidates but I'll say Newsom and DiSantis are significantly better than Trump v Biden. With Trump and Biden, one is unfit to serve and the other is incapable. Yes, that's a low bar but it is a significant one.

I'm not liking the signs I'm seeing. Have returned from a trip to the middle of the country and can confirm they are still deeply passionate about Trump. Plus his recent rallies attract a crowd which DeSantis can only imagine to happen. DeSantis is a better brawler than Trump but he lacks the same snake oil salesman charm. Unless Trump is indicted or something happens to his health or some other reason he can't run, or DeSantis and his supporters somehow persuade Trump not to run (good luck with that), I'm beginning to think the reality is it will be Trump.

Meanwhile Biden is pretty much gone. There was always a question whether he was going to be able to run again in 2022 but the most recent teleprompter and other issues make it apparent he is deteriorating quickly now. His media allies are openly questioning his competence now. His poll ratings have completely collapsed. Because of really really bad choices the Rs made the Ds may still hold the Senate but they are headed into a really bad collapse in the house and on the state levels for which Biden will get the blame.

BTW we really are living in two Americas now. Saw first hand one America that no one wears a mask (even in situations that make me uncomfortable and where vax uptake isn't very high) and that is celebrating the end of Roe and that during the 4th celebrations breaks into rousing chants of "let's go Brandon", and now one in Los Angeles where people are blocking the freeways for Roe and 1/2 the people in the markets are wearing masks again. I'm really beginning to question how the country can stay together under such circumstances, when everything the other 1/2 of the country does is such an existential threat.

 

[crush]

I'm not liking the signs I'm seeing. Have returned from a trip to the middle of the country and can confirm they are still deeply passionate about Trump. Plus his recent rallies attract a crowd which DeSantis can only imagine to happen. DeSantis is a better brawler than Trump but he lacks the same snake oil salesman charm. Unless Trump is indicted or something happens to his health or some other reason he can't run, or DeSantis and his supporters somehow persuade Trump not to run (good luck with that), I'm beginning to think the reality is it will be Trump.

Meanwhile Biden is pretty much gone. There was always a question whether he was going to be able to run again in 2022 but the most recent teleprompter and other issues make it apparent he is deteriorating quickly now. His media allies are openly questioning his competence now. His poll ratings have completely collapsed. Because of really really bad choices the Rs made the Ds may still hold the Senate but they are headed into a really bad collapse in the house and on the state levels for which Biden will get the blame.

BTW we really are living in two Americas now. Saw first hand one America that no one wears a mask (even in situations that make me uncomfortable and where vax uptake isn't very high) and that is celebrating the end of Roe and that during the 4th celebrations breaks into rousing chants of "let's go Brandon", and now one in Los Angeles where people are blocking the freeways for Roe and 1/2 the people in the markets are wearing masks again. I'm really beginning to question how the country can stay together under such circumstances, when everything the other 1/2 of the country does is such an existential threat.

A little more time Grace T and all the TRUTH will be revealed. I see your starting to wake up and that is good. We have New York and California vs the Rest of The States. Bronze Bruce is the Ghost in the machine. The Military will have to help us straighten out the great divide. TDS runs deep in our country and Joe and Hunter sold us all out to the CCP and Marxist. Nancy is in Italy seeing her family at a place that does not share the price of the cost. San Francisco is trash now. I just had another friends dd quit her college and is now safe in Florida.

 

[crush]

 

[espola]

I'm not liking the signs I'm seeing. Have returned from a trip to the middle of the country and can confirm they are still deeply passionate about Trump. Plus his recent rallies attract a crowd which DeSantis can only imagine to happen. DeSantis is a better brawler than Trump but he lacks the same snake oil salesman charm. Unless Trump is indicted or something happens to his health or some other reason he can't run, or DeSantis and his supporters somehow persuade Trump not to run (good luck with that), I'm beginning to think the reality is it will be Trump.

Meanwhile Biden is pretty much gone. There was always a question whether he was going to be able to run again in 2022 but the most recent teleprompter and other issues make it apparent he is deteriorating quickly now. His media allies are openly questioning his competence now. His poll ratings have completely collapsed. Because of really really bad choices the Rs made the Ds may still hold the Senate but they are headed into a really bad collapse in the house and on the state levels for which Biden will get the blame.

BTW we really are living in two Americas now. Saw first hand one America that no one wears a mask (even in situations that make me uncomfortable and where vax uptake isn't very high) and that is celebrating the end of Roe and that during the 4th celebrations breaks into rousing chants of "let's go Brandon", and now one in Los Angeles where people are blocking the freeways for Roe and 1/2 the people in the markets are wearing masks again. I'm really beginning to question how the country can stay together under such circumstances, when everything the other 1/2 of the country does is such an existential threat.

Are you suggesting that people in the"middle of the country" are stupid?

 

[crush]

Are you suggesting that people in the"middle of the country" are stupid?

No, she is saying they don't live and think like you Espola and they do believe in God, unlike you.

 

[crush]

 

[crush]

San Francisco children walk past open-air drug den on way home from school, shocking video shows: report



Their people suffer and their leader is chilling on a nice beach in Italy with her hubby Paul. What State is stupid Espola?

 

[crush]

Hunter's phone is now online at 4Chan for all to see. Here is a pic of Hunter with one of his mentors George Soros. The same guy who said he became a Christian only to rat out his Jewish neighbors and send them to the gas chamber as a Hitler youth snitch.

 

[crush]

 

[crush]

Slaves!!!!

 

[crush]

Sick Monsters!!!

Fitton: Documents show Obama FDA buying fetal heads 'fresh, never frozen' - Judicial Watch

Judicial Watch President Tom Fitton joined @One America News Network to discuss a new batch of documents given to Judicial Watch show how the Obama FDA were buying fetal heads ‘fresh, and never frozen.’ WATCH NOW! We have joined Parler and Rumble! Follow us @JudicialWatch to stay updated on the...

www.judicialwatch.org

 

[crush]

NEW — "John McEnroe on Biden not allowing unvaccinated Djokovic into America to play in the US Open: "These politicians are getting in the way too much. They did it in Australia. Let's let the guy come in and play in the U.S. I mean, c'mon, this is ridiculous!"'

 

[EvilGoalie 21]

Here's another entry for the "no long term studies, kids have no risk" file.

Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation

Mild respiratory COVID causes neuroinflammation and multi-lineage cellular dysregulation in the central nervous system, a phenomenon mirroring cancer-therapy-related cognitive impairment.

www.cell.com

The paper has an interesting back story. One of the senior authors has devoted their career to understanding "brain fog/neuro-sensory problems" in cancer patients treated with old school chemotherapy drugs like methotrexate. The observation was that those symptoms match the range of chronic neuroinflammatory sequalae currently being lumped together as "long Covid". So they used their existing body of data to see if there were similar underlying molecular/cellular mechanisms. And that appears to be the case. If your immune system is configured in a susceptible way, Cov2 is like chemotherapy.

The results are that even mild Cov2 infection in terms of respiratory symptoms can induce substantial neuroinflammation. The paper identifies microglia, which are cytokine secreting cells in the CSF, as being activated by Cov-2 infection. The CSF cytokines secreted by microglia act to inhibit a population of brain cells called astrocytes which are responsible for myelination of neurons. And if the myelination is reduced neurons become more prone for cell death. That's what spelled out in the abstract.

Importantly, the age structure/risk factors for serious respiratory C19 don't correlate with what is emerging as persistent neuroinflammatory problems associated with Cov-2 infection, which range from annoying to long term debilitating. Long term consequences is anybody's guess. The importance of this work is that with specific molecules and cell populations to look at it should be possible to tease that apart more quickly and see to what extent current vaccines reduce CSF cytokine storms like they clearly do with the humoral IL6 circuit. And it will be important to see what's going on with infected kids/young adults. It could work out either way. There's lots of CNS plasticity in young people compared to us old timers. That neuronal plasticity could help circumvent the effects of CoV-2-induce CSF hyperinflammation. Or it could make the developmental processes of establishing neuronal hook ups more susceptible. We'll just have to see.

 

[kickingandscreaming]

I'm not liking the signs I'm seeing. Have returned from a trip to the middle of the country and can confirm they are still deeply passionate about Trump. Plus his recent rallies attract a crowd which DeSantis can only imagine to happen. DeSantis is a better brawler than Trump but he lacks the same snake oil salesman charm. Unless Trump is indicted or something happens to his health or some other reason he can't run, or DeSantis and his supporters somehow persuade Trump not to run (good luck with that), I'm beginning to think the reality is it will be Trump.

Meanwhile Biden is pretty much gone. There was always a question whether he was going to be able to run again in 2022 but the most recent teleprompter and other issues make it apparent he is deteriorating quickly now. His media allies are openly questioning his competence now. His poll ratings have completely collapsed. Because of really really bad choices the Rs made the Ds may still hold the Senate but they are headed into a really bad collapse in the house and on the state levels for which Biden will get the blame.

BTW we really are living in two Americas now. Saw first hand one America that no one wears a mask (even in situations that make me uncomfortable and where vax uptake isn't very high) and that is celebrating the end of Roe and that during the 4th celebrations breaks into rousing chants of "let's go Brandon", and now one in Los Angeles where people are blocking the freeways for Roe and 1/2 the people in the markets are wearing masks again. I'm really beginning to question how the country can stay together under such circumstances, when everything the other 1/2 of the country does is such an existential threat.

I'm sorry to hear about the passion for Trump. He has done an amazing job of harnessing the open and celebrated contempt directed toward large segments of the population.

It will be interesting to see how the COVID "migration" plays out. Previously, movement from CA and NY to "red" states tended to make them less red - although I never saw any studies indicating that was the source of the change. I am wondering if the political leanings of those that moved weren't further right and the COVID migration will tend to increase the political divide between states.

As you say, "everything the other 1/2 of the country does is such an existential threat." and as our resident wannabe-woke hermit says - Are you suggesting that people in the"middle of the country" are stupid? I'm not sure how we overcome this level of division. I'm to the point where I think we need to consider some type of independence of states.

 

[crush]

I'm to the point where I think we need to consider some type of independence of states.

No, we need Nations first to be respected. The Global Elite assholes who control us want a Liberal World Order. Not a New World Order, only Liberal only world, which = no God allowed! Agnostic people don't get it yet and that is not a knock on you brother, it's just the facts. This is Gods planet not Klause and his crew or Hollywood. You see the Light someday and then we can have that beer....lol. Love you man and God wins!

 

[watfly]

Here's another entry for the "no long term studies, kids have no risk" file.

Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation

Mild respiratory COVID causes neuroinflammation and multi-lineage cellular dysregulation in the central nervous system, a phenomenon mirroring cancer-therapy-related cognitive impairment.

www.cell.com

The paper has an interesting back story. One of the senior authors has devoted their career to understanding "brain fog/neuro-sensory problems" in cancer patients treated with old school chemotherapy drugs like methotrexate. The observation was that those symptoms match the range of chronic neuroinflammatory sequalae currently being lumped together as "long Covid". So they used their existing body of data to see if there were similar underlying molecular/cellular mechanisms. And that appears to be the case. If your immune system is configured in a susceptible way, Cov2 is like chemotherapy.

The results are that even mild Cov2 infection in terms of respiratory symptoms can induce substantial neuroinflammation. The paper identifies microglia, which are cytokine secreting cells in the CSF, as being activated by Cov-2 infection. The CSF cytokines secreted by microglia act to inhibit a population of brain cells called astrocytes which are responsible for myelination of neurons. And if the myelination is reduced neurons become more prone for cell death. That's what spelled out in the abstract.

Importantly, the age structure/risk factors for serious respiratory C19 don't correlate with what is emerging as persistent neuroinflammatory problems associated with Cov-2 infection, which range from annoying to long term debilitating. Long term consequences is anybody's guess. The importance of this work is that with specific molecules and cell populations to look at it should be possible to tease that apart more quickly and see to what extent current vaccines reduce CSF cytokine storms like they clearly do with the humoral IL6 circuit. And it will be important to see what's going on with infected kids/young adults. It could work out either way. There's lots of CNS plasticity in young people compared to us old timers. That neuronal plasticity could help circumvent the effects of CoV-2-induce CSF hyperinflammation. Or it could make the developmental processes of establishing neuronal hook ups more susceptible. We'll just have to see.

Would this be a valid reason for and justify closing schools?

Are mice studies applicable to humans?

Why animal studies are often poor predictors of human reactions to exposure - PMC

www.ncbi.nlm.nih.gov

 

[Tyler Durden]

The elite control both political sides and harness emotion and race to divide so that they can take more profits. All this media and article writing is political theater.

 

[EvilGoalie 21]

Are mice studies applicable to humans?

See Figure 5.

Would this be a valid reason for and justify closing schools?

I made one "here's what I'd do if I ran the zoo" policy IMO on this thread. I did the post just before the delta summer of death. I ended up feeling I have the luxury of not having to make those calls, to deal with the tradeoffs, and to live dwelling on outcomes.

So for the school shutdown I choose to only speak for my family. There were pros and cons. With my younger daughter it was frustrating at times, she has pretty serious ADHD. In being forced to get down in the trenches and deal with that I got to discover how her mind worked-what learning was for her. I think we have a much closer relationship now in some ways than before the pandemic, for which I'm grateful. It was of course hard, but we took lemons and made lemonade and tried to have some fun. I came away with an enhanced appreciation for what elementary school teachers do. So what's justified or not justified? The way I might frame the question and make the necessary value calls is probably different than you would. There is no one answer. It was what it was and will likely be again in the coming decades. I do think we will have more geographically tailored public health polices next time and that may be helpful.

 

[crush]

So for the school shutdown I choose to only speak for my family. There were pros and cons. With my younger daughter it was frustrating at times, she has pretty serious ADHD. In being forced to get down in the trenches and deal with that I got to discover how her mind worked-what learning was for her. I think we have a much closer relationship now in some ways than before the pandemic, for which I'm grateful. I

And guess where ADHD came from Evil? WTF did Autism come from? Start connecting the dots and please, get off the Juice brother! I'm super stoked to hear you got closer to your dd and that is awesome. My son was pissed off having to come home and live in my living for room 18 months doing online college. My dd is a social butterfly and got two years stolen. It's all been a blessing but when you go through discipline like we all did, it will produce righteousness for those who have been trained by it and bitterness for those who fight it.

 

[crush]

NEW - U.S. set to extend COVID "health emergency" on Friday, according to media reports.

 

[EvilGoalie 21]

I'm sorry to hear about the passion for Trump. He has done an amazing job of harnessing the open and celebrated contempt directed toward large segments of the population.

It will be interesting to see how the COVID "migration" plays out. Previously, movement from CA and NY to "red" states tended to make them less red - although I never saw any studies indicating that was the source of the change. I am wondering if the political leanings of those that moved weren't further right and the COVID migration will tend to increase the political divide between states.

As you say, "everything the other 1/2 of the country does is such an existential threat." and as our resident wannabe-woke hermit says - Are you suggesting that people in the"middle of the country" are stupid? I'm not sure how we overcome this level of division. I'm to the point where I think we need to consider some type of independence of states.

Compared to Grace, I came away from my latest mid-American juant with a more hopeful feel for the American project compared to previous trips. Sampling error maybe. For your last point, you might consider reading Colin Woodward's "American Nations". It's a great book and actually benefits from being written before the Trump catalyst. The basic thesis is that America was colonized by essentially a rando set of refugees with different political outlooks who have been battling each other ever since, forming coalitions leading to the "red" vs "blue" stalemate we have today. The last chapter of the book deals with possible outcomes-ways to possibly stop fighting with each other. One interesting suggestion is a type of EU model, with considerable autonomy between these "nations" but with collective economic and defense obligations. I suspect it would need to be more a city-state vs hinterlands type of arrangement as opposed to current state boundaries, which, once you get past the eastern seaboard, are pretty arbitrary. Of course it is all pie in the sky since nobody is going to be agreeing on much of anything for the immediate future.