Vaccine

Speaking of the vaccine (s) now comes the push for boosters.

What is surprising to me is that the current Pfizer booster or 3rd shot is the same thing as their original two shots, same formula so how does that help vs the delta or variants?

The original shot appears to gives some protection against delta. Getting the booster just triggers our immune system again as it is feared the protection wanes over time.
 
Speaking of the vaccine (s) now comes the push for boosters.

What is surprising to me is that the current Pfizer booster or 3rd shot is the same thing as their original two shots, same formula so how does that help vs the delta or variants?


Its a good question.

With the mRNA and, to a somewhat lesser extent, adeno vaccine platforms it would be possible to have boosters that incorporate the most recent genetic changes identified in emerging variants. The vaccine particles could even contain a mixture of mRNAs encoding all known S protein variants. It is one of the advantages of the technology. From a regulatory standpoint, however, this would require a more streamlined approval process. And it would require a manufacturing process that could implement such changes at scale.

Why boosters if not directed specifically against delta? There are many ethical and practical immunological issues surrounding boosters. But from an epidemiological standpoint, it's a numbers game. The idea is to curb the spread of delta or whatever (almost certainly smaller if it comes at all) wave may come next. Basically, to reduce the total viral load in the population, thereby limiting the potential of new variants arising. Regardless of whether your initial immune priming was through vaxx or infection, the booster keeps circulating antibody levels high. Against a high burst variant like delta this won't stop community transmission but it does reduce burst size. So, say the R0 measure for delta infectivity goes from 6 to R(effective) of 3. Instead of one person infecting, on average, 6 they infect 3. The wave is still growing. But, since the total number of cases is a geometric expansion based on the R value, in 10 infection cycles that means a theoretical reduction in total cases from about 10000000 to 20000. That's the numbers game and the question becomes whether to play that game or not.
 
Speaking of the vaccine (s) now comes the push for boosters.

What is surprising to me is that the current Pfizer booster or 3rd shot is the same thing as their original two shots, same formula so how does that help vs the delta or variants?

 
We don’t need to wonder what happens if you open up everything and tell people masks are a personal choice.

We can look at Arizona. Your covid policy did all that, and it was a complete train wreck.Arizona mask mandate.jpg

Maybe, if you all were Mormon, it would have been like Utah. But you aren’t, and it wasn’t.
You sound desperate to perpetuate your religion.
 
Dizzy, by now we all know you’re just reposting graphs you do not understand, but found on some right wing website.

Glad to hear you now approve of cluster RCT. Does that mean you’re willing to admit that surgical masks work to reduce effective transmission?
 
Keith got his 3rd shot booster jab. I think his last shot was bath salt. This guy has lost his mind. I used to watch him before he got all weirdo on us. Dr. Fraud say's now that to be 100% FULLY vaccinated ((obedient)). you need the third booster. I'm too scared of shot #1 and he's right, I have no idea wtf is in these jabs.

 
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