Bruddah IZ
DA
Speaking of underpowered, why are you avoiding looking at the data from the last 20 to 50 years of upper respiratory diseases instead of just the last year and a half? Not to mention the use of the PCR test that only finds dead pieces of nucleotides that become "cases" while IFR, updated in March of 2021, worse case is .00008 for the school children that L.A. wants to mask? Leveraging fear with an IFR of .00008 is just plain old stupid and an indictment of our publication education system.Sample size is pretty darn small. Only 5% of participants were previously infected.
They were trying to draw conclusions from a sample size of 1220 previously infected but recently vaccinated patients. It is no surprise that they couldn’t get a significant result. The study was completely underpowered.
This is why their confidence interval was “0 to infinity” for the previously infected group. The data didn’t say anything this time.
You’d need a considerably larger study to say anything other than “we don’t know.”. Preferably in India, where you can find out about the value of the vaccine against a new variant.
I really wish they would stop printed underpowered studies as proof of a negative. There is a statistical standard for demonstrating the lack of a correlation. This study does not meet it.