Nothing is not the right word to use. Can we say for sure what the overall impact is, no. I've said from the very beginning, a rational discussion on the topic of AGW should not involve any absolutes. Good Science evolves and changes as new information comes to light.
The important thing is to discuss what is reasonable based on what we currently know.
If we have to argue about what we currently know, for political and profiteering reasons, then we can't have a discussion and that's what's going on here.